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From gut to brain: short-term ketogenic diet alleviates stat...

From gut to brain: short-term ketogenic diet alleviates stat...

최근 학술지에 게재된 연구에 따르면, 연구진은 관찰 연구를 통해 Rats with epilepsy were fed a KD or a normal diet (ND) for 4 weeks. Following the lithium-pilocarpine-induced status epilepticus (SE), an assessment of cognitive function was performed using the Mor 그 결과, On the probe trials of the MWM, rats in the KD group showed significantly shorter escape times (P < 0.001) and spent more time in the target quadrant (P < 0.05) compared to rats in the ND group. KD was associated with reduced microbial richness compared to ND, as well as distinct differences in gut microbiota composition across phyla, families, and genera. The KD group had significantly lower 연구팀은 "In epileptic rats, short-term use of the KD may modulate gut microbiota and enhance cognition. Shifts in gut microbiota are associated with changes in neurotransmitters and amino acids. Further investigation is warranted into the microbiota-gut-br"라고 결론지었다. 이번 연구의 의의는 해당 분야에 새로운 통찰을 제공했다. 다만 연구진은 장기적 효과는 추가 연구가 필요하다고 밝혔다.