Role of Micronutrients in Perioperative Care: A Systematic R...
📅 2026년 5월 18일📰 Indian J Crit Care Med👀 조회 2
최근 학술지에 게재된 연구에 따르면, Micronutrient adequacy is essential for wound healing, immune competence, antioxidant defense, and erythropoiesis, all critical to perioperative recovery. Deficiencies in iron, vitamin C, vitamin D, selenium, and zinc are common in surgical patien 연구진은 무작위 대조군 시험를 통해 A PRISMA-based systematic review of major databases and trial registries (through August 2025) included randomized controlled trials (RCTs) and observational studies assessing endpoints such as woun 그 결과, Twenty-two studies met the inclusion criteria. Intravenous iron consistently increased hemoglobin and iron stores but showed variable transfusion effects. Vitamin C supplementation reduced perioperative pain and modestly improved wound healing. Selenium normalization did not translate into outcome benefits. Low vitamin D and zinc levels were associated with higher infection rates and delayed 연구팀은 "Routine high-dose supplementation is not justified. Targeted preoperative screening and correction of iron, vitamin D, zinc, and selenium deficiencies may improve recovery in high-risk surgical patients. Further large, standardized trials are need"라고 결론지었다. 이번 연구의 의의는 무작위 배정으로 인과관계를 보다 명확히 규명했다. 다만 연구진은 장기적 효과는 추가 연구가 필요하다고 밝혔다.
A recent study published in a peer-reviewed journal reveals that Micronutrient adequacy is essential for wound healing, immune competence, antioxidant defense, and erythropoiesis, all critical to perioperative recovery. Deficiencies in iron, vitamin C, vitamin D, selenium, and zinc are common in surgical patien The researchers conducted a randomized controlled trial to investigate A PRISMA-based systematic review of major databases and trial registries (through August 2025) included randomized controlled trials (RCTs) and observational studies assessing endpoints such as woun Results showed that Twenty-two studies met the inclusion criteria. Intravenous iron consistently increased hemoglobin and iron stores but showed variable transfusion effects. Vitamin C supplementation reduced perioperative pain and modestly improved wound healing. Selenium normalization did not translate into outcome benefits. Low vitamin D and zinc levels were associated with higher infection rates and delayed The authors concluded, "Routine high-dose supplementation is not justified. Targeted preoperative screening and correction of iron, vitamin D, zinc, and selenium deficiencies may improve recovery in high-risk surgical patients. Further large, standardized trials are need" This study is significant as it establishes causality through randomization. However, the researchers noted that long-term effects require further investigation.
